Piraeus is the gateway to Athens, the "Cradle of Western Civilization," famed for its lasting cultural and political influence. Driven by tourism and the 2004 Olympics, Greece has redeveloped many sites. Athens remains a historian's delight, with the Acropolis, Parthenon, Plaka's winding streets, the Temple of Olympian Zeus, the Temple of Athena Nike, and the Archaeological Museum's renowned ancient artifacts.

Chania wears its past on its sleeve. Spend the day in museums, from those uncovering the ancient history buried beneath the rocky soil to those celebrating Greece's magnificent maritime history and the region's unique folklore. Visit the ruins of the city-state of Aptera, a powerhouse in Minoan and Hellenistic times and eventually a Roman stronghold.

Malta's capital and major port, Valletta was inscribed as a UNESCO World Heritage Site in 1980. Highlights include the 19th-century Mosta Dome, San Anton Palace Gardens in Attard, Lija and Balzan, and the sea views from Dingli Cliffs. Valletta also makes a good base for day trips to Mdina, with St. John's Baroque Cathedral, and Rabat, once part of Roman Melita, with its archaeological sites.

With archaeological sites like Selinunte and Segesta; the mountaintop medieval town of Erice, overlooking the Egadi archipelago; and nearby Marsala, with its House of Mosaics and renowned wine, Trapani lets visitors experience Sicily with all their senses. Don't miss a day trip through the scenic countryside to local olive farms, where cooking demonstrations become delicious repasts and lasting gastronomic memories.

Savor this delightful old city spread over seven hills and its many attractions reflecting the influence of its numerous rulers. Climb to the citadel; visit the fabulous Archaeological Museum, Roman ruins and Pisan towers, early Byzantine churches, the Cathedral or the Botanic Gardens. Enjoy the nearby beach or discover the remains of Sardinia's ancient, enigmatic Nuraghe culture, their villages and huge burial caves.

Mallorca, also known as Majorca, is a wind-swept island with steep jagged cliffs and olive groves more than a thousand years old. Mallorca is an island of contrasts. To the south is a busy tourist area with hotels, bars, restaurants, shopping and dazzling night life. To the north are rocky valleys, sleepy villages shrouded in bougainvillea, and breathtaking views. Palma is dominated by the breathtaking Gothic Cathedral, located high above the waterfront on the site of a former mosque.

One of Europe's most visually stunning cities, Barcelona balances the medieval intimacy of its Gothic Quarter with the grace and distinction of the wide boulevards in the Moderniste Eixample. It was the home of architect Antoni Gaudí, whose Sagrada Familia Cathedral, Park Güell and Casa Milà are the most profound statements of Modernisme. View the splendid works at the Picasso Museum and the Miro Foundation, or discover Barcelona's passionate ambiance at a flamenco show.

Experience Costa Brava and understand why Salvador Dalí and others have long been inspired by its beaches and coves. Spend a day in the warm sand of La Fosca or learning about the history of this fishing village in Museu de la Pesca or simply taking in the Mediterranean air while walking down the promenade. Just an hour north of the city, you can visit the extraordinary Dalí Theatre-Museum in Figueres. The museum holds works done from his adolescence to the last years of his life.

Enjoy the exquisite Provençal countryside beyond the resort, with charming villages, narrow stepped streets, lovely churches, and stunning views. Visit a local winery or drive along the rugged coast for landscapes, beaches, islands, and the Massif des Maures. Browse elegant boutiques for French perfume, fine jewelry, fashion, and leather goods. Try local lobster with chilled white wine or lavender ice cream.

Tiny but packed with fun, Monte Carlo blends history, beauty, entertainment, and leisure. Monaco's wealthiest district, it's known as the international capital of luxury, with celebrity sightings, casinos, and nightlife. Yet its old-world charm remains in art and architecture: palaces, cathedrals, and museums in a historic old town. Don't miss the daily changing of the guard and the public areas of the Palais du Prince, home to the royal family and once to Grace Kelly.

Picturesquely set in a narrow cove, this tiny port is famed for its beautiful setting, mild climate, and lush vegetation. Crowded around a small harbor, it is among the most beautiful Mediterranean ports and a longtime haunt of the wealthy, artists, and actors. Don't miss Chiesa di San Giorgio and Castello Brown with its garden and harbor views.

Livorno in Tuscany is a gateway to Florence and Pisa. From the 13th to 16th centuries, Renaissance freedom inspired Dante, Donatello, Michelangelo, Giotto, Botticelli, da Vinci, and Machiavelli. In Florence, see the Galleria dell'Accademia and Michelangelo's David, plus the Uffizi, Italy's famed art gallery. Visit Pisa's Campo dei Miracoli, Siena's medieval charm, and Lucca, where you can bike through the Tuscan countryside.

Rome offers endless choices: enjoy street performers at the Spanish Steps, wine and people-watching in colorful Trastevere, or the city's rich history and architecture. St. Peter's Basilica is a full-day visit, with the Sistine Chapel and panoramic views from the dome. Don't miss the Trevi Fountain, the Colosseum, and Aventine Hill, which overlooks the Imperial Palaces ruins and the Circus Maximus.