Rome offers endless choices: enjoy street performers at the Spanish Steps, wine and people-watching in colorful Trastevere, or the city's rich history and architecture. St. Peter's Basilica is a full-day visit, with the Sistine Chapel and panoramic views from the dome. Don't miss the Trevi Fountain, the Colosseum, and Aventine Hill, which overlooks the Imperial Palaces ruins and the Circus Maximus.

As is true of the rest of the Amalfi Coast, this city boasts beautiful vistas, charming open-air cafés and captivating landmarks with historic roots. One example is Duomo di Salerno, an absolute must see for lovers of art, history and architecture. This Italian cathedral showcases an impressive design, powerful frescoes and melodious mosaics spanning the centuries as far back as the 11th century, when it was built by the Normans.

Messina, Sicily's third-largest city, was a key medieval port for knights heading to the Crusades. Though extensively rebuilt, it still has major landmarks, especially the cathedral with its unusual astronomical clock, the 12th-century Catania Church, and the ornate Teatro Vittorio Emanuele. It's also a starting point for day trips to Mt. Etna's Crateri Silvestri.

Malta's capital and major port, Valletta was inscribed as a UNESCO World Heritage Site in 1980. Highlights include the 19th-century Mosta Dome, San Anton Palace Gardens in Attard, Lija and Balzan, and the sea views from Dingli Cliffs. Valletta also makes a good base for day trips to Mdina, with St. John's Baroque Cathedral, and Rabat, once part of Roman Melita, with its archaeological sites.

Kotor is a coastal town in Montenegro, located in a most secluded part of the Gulf of Kotor. The old port, surrounded by an impressive city wall built by the House of Nemanjicc, is very well preserved and is a UNESCO World Heritage site. Numerous other attractions include the Cathedral of Saint Tryphon in the old town (built in 1166), and ancient walls which stretch directly above the city. Nightlife also attracts tourists to Kotor with pubs, taverns, cafes, and nightclubs.

Known as the "Pearl of the Adriatic," Dubrovnik was founded in the 7th century by a group of refugees from Epidaurum (today's Cavtat). It is known worldwide for its unique marble-paved squares, tall houses, steep-cobbled streets and fountains. The city walls, once used to as protection against its enemies, now keep motorists at bay in this picturesque town. UNESCO named the Old City a World Heritage Site, and Dubrovnik's beautiful historic sites have been restored to their former glory.

The rich history and vibrant culture of Rijeka left its mark in countless sites. Beginning with Trsat Castle and its magnificent views of Rijeka's Old City to the bustling Korzo pedestrian promenade with its numerous cafés and bars, this is one of Europe's hidden treasures. Learn about the city's long relationship with the sea at the Maritime and History Museum, which is housed in the former palace of the Austro-Hungarian governor, replete with grand staircases and glittering chandeliers.

From Fusina, journey to Venice, where you'll witness the Grand Canal, lined with enchanting Renaissance architecture. Art lovers can visit the Peggy Guggenheim Collection or the Doge's Palace, a Gothic masterpiece. Savor Venetian cuisine at a traditional trattoria, sampling fresh local dishes. History enthusiasts can also peruse St Mark's Basilica, a marvelous 18th-century cathedral adorned with sculptures, mosaics and bas-reliefs representing Italian sophistication.

The rich history and vibrant culture of Rijeka left its mark in countless sites. Beginning with Trsat Castle and its magnificent views of Rijeka's Old City to the bustling Korzo pedestrian promenade with its numerous cafés and bars, this is one of Europe's hidden treasures. Learn about the city's long relationship with the sea at the Maritime and History Museum, which is housed in the former palace of the Austro-Hungarian governor, replete with grand staircases and glittering chandeliers.

Split is the largest Croatian city on the Adriatic coast. It is famous for Diocletian's Palace, built as the Roman emperor's retirement home; its stone structure, grounds, and cellars are a major highlight. Other sights include the Cathedral of St. Duje, on the remains of an ancient shrine said to be the world's oldest, and the Mestrovic Gallery, featuring works by Croatian sculptor Ivan Mestrovic in his former home and atelier.

Perched on the Adriatic Sea, the Italian city of Bari has long served as an important port city for both ancient and modern Italy. Today, its rich past attracts visitors from around the world. The Basilica of Saint Nicholas, built in 1087, holds the remains of its namesake beneath the altar, while the Petruzzelli Theatre is one of the grandest opera houses in the country.

Igoumenitsa's port is like a Greek accordion: expanding, contracting, sometimes silent, but always finding its voice. Founded in the 4th century BC as a key town in Thresprotia, destroyed in World War II after Axis occupation, it has repeatedly rebounded. Today it is a major tourism port, welcoming ferry passengers from across Europe to begin their Greek holidays. Let Igoumenitsa's song welcome you too.

Step back in time at Ancient Olympia, the birthplace of the Olympic Games - now deemed a UNESCO World Heritage Site. Relive the roaring cheers of the spectators as the athletes took their marks on the marble starting blocks, and picture the temples, the treasuries, the porticoes and statues as they were.

Monemvasia's Old Town sits on a monolithic island nicknamed the "Gibraltar of the East," a natural fortress that preserved it through time. Cross a narrow causeway to the only entrance to this carefully restored medieval walled town. Wander its car-free cobblestone alleys for a rare glimpse of Greece untouched by time and tourism, then dine with a view on local specialties like fresh pasta, cheese pies, and malvasia, its famed sweet wine.

Mykonos, steeped in Greek myth, was named after Apollo's grandson, Mykons, and linked to the battle between Zeus and the Gigantes. Today it's one of Greece's most beloved destinations, known for its postcard scenery and lively nightlife. It showcases classic Cycladic architecture, with even new buildings required by law to match the whitewashed, cube-like style. Visit Little Venice, Paraportiani Church, and the Delos archaeological site.

Piraeus is the gateway to Athens, the "Cradle of Western Civilization," famed for its lasting cultural and political influence. Driven by tourism and the 2004 Olympics, Greece has redeveloped many sites. Athens remains a historian's delight, with the Acropolis, Parthenon, Plaka's winding streets, the Temple of Olympian Zeus, the Temple of Athena Nike, and the Archaeological Museum's renowned ancient artifacts.