Piraeus is the gateway to Athens, the "Cradle of Western Civilization," famed for its lasting cultural and political influence. Driven by tourism and the 2004 Olympics, Greece has redeveloped many sites. Athens remains a historian's delight, with the Acropolis, Parthenon, Plaka's winding streets, the Temple of Olympian Zeus, the Temple of Athena Nike, and the Archaeological Museum's renowned ancient artifacts.

Chania wears its past on its sleeve. Spend the day in museums, from those uncovering the ancient history buried beneath the rocky soil to those celebrating Greece's magnificent maritime history and the region's unique folklore. Visit the ruins of the city-state of Aptera, a powerhouse in Minoan and Hellenistic times and eventually a Roman stronghold.

Santorini's dramatic views-whitewashed houses clinging to the caldera, plus white, red, and black-sand beaches-make it one of the world's most photographed places. Visit Ancient Akrotiri, a town preserved by ash from an eruption 3,600 years ago, and take a day trip to Palea (Old) Kameni and Nea (New) Kameni, two black-lava islands in the center of the Santorini basin.

Mykonos, steeped in Greek myth, was named after Apollo's grandson, Mykons, and linked to the battle between Zeus and the Gigantes. Today it's one of Greece's most beloved destinations, known for its postcard scenery and lively nightlife. It showcases classic Cycladic architecture, with even new buildings required by law to match the whitewashed, cube-like style. Visit Little Venice, Paraportiani Church, and the Delos archaeological site.

Located in the southwestern corner of Anatolia, Bodrum is a seacoast town in which sleek yachts are anchored in twin bays beneath the walls of a medieval Crusaders' castle. The town owes its fame to a man long dead (Mausolus) and his famous "Mausoleum," one of the Seven Wonders of the Ancient World. Bodrum's other claim to fame comes from Herodotus, the "Father of History," and the first person to write a comprehensive world history of the West.

Europe's classical metropolis, Ephesus, was one of the largest cities in all of the Roman Empire, boasting one of the Seven Wonders of the Ancient World, the Temple of Artemis. Explore the ruins of its massive Theater, the Temple of Hadrian and the magnificent Celsus Library.

Ancient history meets modern cable cars in Pergamum, one of Turkey's top archaeological sites. From the hilltop Acropolis, enjoy sweeping views and see monuments including an altar likely dedicated to Zeus and Athena plus a theater for 10,000. Afterward, try kofte and olive-oil eggplant. You can also head to Izmir's Kemeralti Market for textiles, rugs, and jewelry, or relax on Dikili's golden beaches.

The tiny island of Bozcaada floats peacefully off the western coast of Turkey in the Dardanelles Strait that connects the Marmara to the Aegean. This charming port boasts untouched bays with a rich marine life, delightful local culture, significant historical heritage, and world-class wine.

Once serving as the capital of the Ottoman and Byzantine Empires, Istanbul today offers impressive architecture, historic sites, dining, shopping, nightlife and exotic atmosphere. Spend time in the Old City to explore renowned places, like the Hagia Sophia, Blue Mosque and Topkapi Palace.

Once serving as the capital of the Ottoman and Byzantine Empires, Istanbul today offers impressive architecture, historic sites, dining, shopping, nightlife and exotic atmosphere. Spend time in the Old City to explore renowned places, like the Hagia Sophia, Blue Mosque and Topkapi Palace.