Sunny Florida skies, year-round warmth, nightlife, and a diverse culture define this cosmopolitan city. South Beach draws crowds, while the Art Deco District is the world's largest collection of Art Deco architecture. Shop from Bal Harbour to Lincoln Road and Coconut Grove, enjoy Cuban culture on Calle Ocho, or visit the historic Venetian Pool. There's something for everyone in this "Gateway to the Americas."

This flower-scented little city/island is a haven for famous writers, former hippies, struggling artists, sun seekers, and tourists from all over the world. They like the relaxed pace, the storybook architecture, the carnival-like street life, and they are drawn to Mallory Square every evening to applaud the sunset. The island, just 2 miles wide by 4 miles long, is one of about a thousand coral islets in an archipelago that stretches 126 miles southward from Miami.

From duty-free shopping and Seven Mile Beach to the Cayman Islands National Museum, Pedro St. James National Historic Site, Queen Elizabeth II Botanic Park, and a rum distillery tour, this quaint capital offers something for everyone.

Falmouth offers a lively taste of Jamaica's north coast, where Georgian-era streets meet the easy rhythm of island life. Explore the historic town center, sample jerk flavors and rum punch, or head to nearby beaches and waterfalls for sun and scenery. With its warm hospitality, colorful markets, and coastal charm, Falmouth makes a memorable Caribbean port of call.

Hidden in the southwestern corner of the Dominican Republic, Cabo Rojo is where red cliffs meet electric-blue Caribbean waters in a display of raw, untouched beauty. The contrast of salt flats, rugged coastline and cactus-dotted desert creates a landscape unlike anywhere else on the island. Nearby, Bahía de las Águilas offers miles of powdery sand and some of the clearest water in the Caribbean. This off-the-grid gem draws nature lovers, snorkelers and seekers of true seclusion.

Drive through Manga's residential area to admire late-19th-century Republican-style mansions. Visit Castillo San Felipe de Barajas, once Latin America's most important military fort. Take a boat to the Islas del Rosario-26 coral islands off Isla Barú-and continue to San Martín de Pajarales for the aquarium, dolphin and shark show, and other marine attractions. Then board the Spanish Galleon, a replica 17th-century ship, for a cruise of Cartagena's inner bay.

This bustling city offers open-air markets, striking architecture, and historical museums. In Parque Vargas, amid palms and vine-covered Ficus trees, sloths often move from branch to branch. Ride the aerial tram through Braulio Carrillo National Park's rainforest canopy, or take a boat through the Tortuguero Canals or Estero Negro Estuary, watching for birds, monkeys, iguanas, sloths, crocodiles, and the iridescent Blue Morpho butterfly.

Panama City blends a shimmering skyline with cobblestone streets, rooftop bars, and centuries-old ruins. Founded in 1519, Panamá Viejo was abandoned in the mid-17th century and replaced by Casco Viejo; together they are a UNESCO Cultural World Heritage site. Visit the Panama Canal Museum for exhibits on the "Big Ditch," and honor the 22,000 workers who died building it at Plaza de Francia.