Sunny Florida skies, year-round warmth, nightlife, and a diverse culture define this cosmopolitan city. South Beach draws crowds, while the Art Deco District is the world's largest collection of Art Deco architecture. Shop from Bal Harbour to Lincoln Road and Coconut Grove, enjoy Cuban culture on Calle Ocho, or visit the historic Venetian Pool. There's something for everyone in this "Gateway to the Americas."

From duty-free shopping and Seven Mile Beach to the Cayman Islands National Museum, Pedro St. James National Historic Site, Queen Elizabeth II Botanic Park, and a rum distillery tour, this quaint capital offers something for everyone.

Drive through Manga's residential area to admire late-19th-century Republican-style mansions. Visit Castillo San Felipe de Barajas, once Latin America's most important military fort. Take a boat to the Islas del Rosario-26 coral islands off Isla Barú-and continue to San Martín de Pajarales for the aquarium, dolphin and shark show, and other marine attractions. Then board the Spanish Galleon, a replica 17th-century ship, for a cruise of Cartagena's inner bay.

This small port city on Costa Rica's west coast is a gateway to mountains and wildlife. Cruise the Tárcoles River, home to birds and many crocodiles. In the Puntarenas highlands, see purebred Andalusian horses perform at a hacienda. Travel the Pacific coast to Carara National Park to spot scarlet macaws in rainforests and mangroves. Stroll Paseo de los Turistas by Puntarenas Beach and try a "Churchill," the local snow cone.

Drive into the mountains to beautiful old Antigua, once the country's colonial capital, and discover its lovely bougainvillea-draped buildings and breathtaking views of emerald volcanoes. Travel to famed Lake Atitlan and step back in time as you encounter the indigenous people in all their finery still living along the lakeshore. Whether you opt to explore the ancient Mayan history of the region or it's more-recent colonial past, its architecture, culture and locals are sure to inspire.

Acapulco, the "Pearl of the Pacific," is famed for soaring cliffs, white-sand bays, and the Sierra Madre del Sur. Watch the La Quebrada divers from La Perla at Hotel Mirador, explore the Fort of San Diego and El Zócalo, and visit the botanical garden. Finish with cliffside ceviche: fresh chopped raw fish with peppers and lime.

Cabo San Lucas on Baja's southern tip offers two sides: lively, bar-and-restaurant-filled Cabo and quieter, historic San José del Cabo. Once a sleepy fishing village, Cabo now draws beach vacationers; Playa El Médano is the main draw, and Land's End has Playa del Amor and El Arco. In San José, see a 17th-century Jesuit mission, a bird-filled estuary, and the Art District's cafes and galleries.

Located on the west coast of Baja California, Ensenada is a sportsman's paradise with popular pursuits including surfing, sport fishing, sea kayaking, horseback riding and mountain biking. If you prefer more leisurely activities, take a scenic coastal drive to the Punta Banda Peninsula to see La Bufadora. This marine geyser that shoots from the sea toward the cliffs is one of the largest blowholes in North America. Back in town, pop into famous Hussong's Cantina and sip a margarita in the bar where the cocktail was reputedly invented.

After the Jesuits built a series of missions along the coast of Alta California, the Spaniards established a port in 1781 as a supply stop for their coastal shipping routes. With the arrival of the transcontinental railroad and the discovery of oil, people began to arrive in droves. In 1923 the much-photographed giant letters were erected on the hill, and the golden age of Hollywood was born. The scale of Los Angeles, 90 miles long by 50 miles wide, defies belief.