One of Europe's most visually stunning cities, Barcelona balances the medieval intimacy of its Gothic Quarter with the grace and distinction of the wide boulevards in the Moderniste Eixample. It was the home of architect Antoni Gaudí, whose Sagrada Familia Cathedral, Park Güell and Casa Milà are the most profound statements of Modernisme. View the splendid works at the Picasso Museum and the Miro Foundation, or discover Barcelona's passionate ambiance at a flamenco show.

Discover exotic Arrecife, a relaxed white city set against volcanic landscape on a turquoise bay. Visit Timanfaya National Park, El Charco de San Gines with its colorful fishing boats, the Museum of Modern Art in Castle San Jose, and the Archaeological Museum in Castle San Gabriel. Shop Calle Leon y Castilla for linens, carvings, Guanches pottery, perfume, and liquor, then enjoy tapas and wine by the sea.

Discover Santa Cruz de La Palma: colorful buildings, 18th-century mansions, wrought-iron balconies draped with bougainvillea, volcanic mountains, green valleys, and a turquoise sea. Visit the star-shaped 17th-century Castillo de Santa Catarina and Moorish-influenced Iglesia de El Salvador, stroll O'Daly Street's boutiques and artisan shops, and enjoy fine Canary Island wine.

Old San Juan, the oldest city under U.S. jurisdiction and second-oldest European settlement in the Americas, blends historic landmarks, pristine beaches, great cuisine, and resilience. Walk cobblestoned streets past Spanish Colonial sites, browse colorful plazas, and visit Castillo San Felipe del Morro, Castillo San Cristobal, and Museo de Arte de Puerto Rico. Then explore El Yunque's rainforest and waterfalls before relaxing on Luquillo Beach.

Sunny Florida skies, year-round warmth, nightlife, and a diverse culture define this cosmopolitan city. South Beach draws crowds, while the Art Deco District is the world's largest collection of Art Deco architecture. Shop from Bal Harbour to Lincoln Road and Coconut Grove, enjoy Cuban culture on Calle Ocho, or visit the historic Venetian Pool. There's something for everyone in this "Gateway to the Americas."