Piraeus is the gateway to Athens, the "Cradle of Western Civilization," famed for its lasting cultural and political influence. Driven by tourism and the 2004 Olympics, Greece has redeveloped many sites. Athens remains a historian's delight, with the Acropolis, Parthenon, Plaka's winding streets, the Temple of Olympian Zeus, the Temple of Athena Nike, and the Archaeological Museum's renowned ancient artifacts.

Chania wears its past on its sleeve. Spend the day in museums, from those uncovering the ancient history buried beneath the rocky soil to those celebrating Greece's magnificent maritime history and the region's unique folklore. Visit the ruins of the city-state of Aptera, a powerhouse in Minoan and Hellenistic times and eventually a Roman stronghold.

Malta's capital and major port, Valletta was inscribed as a UNESCO World Heritage Site in 1980. Highlights include the 19th-century Mosta Dome, San Anton Palace Gardens in Attard, Lija and Balzan, and the sea views from Dingli Cliffs. Valletta also makes a good base for day trips to Mdina, with St. John's Baroque Cathedral, and Rabat, once part of Roman Melita, with its archaeological sites.

With archaeological sites like Selinunte and Segesta; the mountaintop medieval town of Erice, overlooking the Egadi archipelago; and nearby Marsala, with its House of Mosaics and renowned wine, Trapani lets visitors experience Sicily with all their senses. Don't miss a day trip through the scenic countryside to local olive farms, where cooking demonstrations become delicious repasts and lasting gastronomic memories.

Savor this delightful old city spread over seven hills and its many attractions reflecting the influence of its numerous rulers. Climb to the citadel; visit the fabulous Archaeological Museum, Roman ruins and Pisan towers, early Byzantine churches, the Cathedral or the Botanic Gardens. Enjoy the nearby beach or discover the remains of Sardinia's ancient, enigmatic Nuraghe culture, their villages and huge burial caves.

Mallorca, also known as Majorca, is a wind-swept island with steep jagged cliffs and olive groves more than a thousand years old. Mallorca is an island of contrasts. To the south is a busy tourist area with hotels, bars, restaurants, shopping and dazzling night life. To the north are rocky valleys, sleepy villages shrouded in bougainvillea, and breathtaking views. Palma is dominated by the breathtaking Gothic Cathedral, located high above the waterfront on the site of a former mosque.

One of Europe's most visually stunning cities, Barcelona balances the medieval intimacy of its Gothic Quarter with the grace and distinction of the wide boulevards in the Moderniste Eixample. It was the home of architect Antoni Gaudí, whose Sagrada Familia Cathedral, Park Güell and Casa Milà are the most profound statements of Modernisme. View the splendid works at the Picasso Museum and the Miro Foundation, or discover Barcelona's passionate ambiance at a flamenco show.