Panama City blends a shimmering skyline with cobblestone streets, rooftop bars, and centuries-old ruins. Founded in 1519, Panamá Viejo was abandoned in the mid-17th century and replaced by Casco Viejo; together they are a UNESCO Cultural World Heritage site. Visit the Panama Canal Museum for exhibits on the "Big Ditch," and honor the 22,000 workers who died building it at Plaza de Francia.

The city blends Dutch and Spanish architecture. Now a Dutch city named for the House of Orange, it became Aruba's capital in 1979. Beyond the beaches, start at Wilhelmina Park, a tropical waterfront garden with Caribbean breezes, then visit the Archaeological Museum of Aruba or the Numismatic Museum of Aruba, which displays coins from 400+ countries. Fort Zoutman (1796), the island's oldest Dutch building, gained Willem III Tower in 1867 and now offers views, music festivals, and craft fairs.

Discover colorful Port of Spain, rich in multicultural heritage, skyscrapers, lush gardens, and early 20th-century mansions. Explore The Savannah, its orchid house, and enjoy a fresh coconut from a park vendor. Visit the National Museum and Art Gallery, The Red House, The Magnificent Seven, and Queen's Royal College's clock tower. Frederick St. offers restaurants, galleries, shopping, local art, fine clothing, and unique souvenirs. Savor seafood, roti, or callaloo with Calypso rhythms.

Manaus, the "Paris of the Jungle," is the capital of Brazil's Amazonas state. Once a river village on the left bank of the Rio Negro, near its meeting with the Amazon, it was shaped by 19th-century rubber barons and is now a key gateway to the mid-Amazon. Riverboats explore tributaries, estuaries, and creeks rich in wildlife. Highlights include the Renaissance-style Opera House and the Customs House, built in Liverpool and nicknamed "Little Big Ben."

Manaus, the "Paris of the Jungle," is the capital of Brazil's Amazonas state. Once a river village on the left bank of the Rio Negro, near its meeting with the Amazon, it was shaped by 19th-century rubber barons and is now a key gateway to the mid-Amazon. Riverboats explore tributaries, estuaries, and creeks rich in wildlife. Highlights include the Renaissance-style Opera House and the Customs House, built in Liverpool and nicknamed "Little Big Ben."

Boca Da Valeria is an Indian village on a 400-ft hill overlooking the Amazon, between Parintins and Santarem. Wander the small settlement or relax aboard and enjoy close-up views of lush equatorial vegetation. Ashore, see log canoes, grass huts, and a life of hunting and fishing unchanged since early explorers. Due to the under-developed nature of this destination, organized tours are not available.

About 25 miles from Santarém, Brazil, Alter do Chão is an Amazon River community on the Rio Tapajós, named for a flat-topped hill backdrop. This small island features white-sand beaches, palm trees, cottages, Indian handicrafts, lush vegetation, a turquoise lagoon, and exceptionally clear water, making it a popular destination. Note: due to its underdeveloped nature, organized tours are not available.

Whether you enjoy climbing waterfalls or simply relaxing on sun-kissed beaches, you will find that the capital of Grenada has something for everyone. From the moment you arrive, you will not only be charmed by a colorful mix of colonial architecture set on lush vegetation, but also be enchanted by the smell of cinnamon and nutmeg. Be sure to visit one of the many spice estates or shop for exotic spices in the Market Square.

Discover a touch of old Amsterdam in a Caribbean paradise. Pastel waterfront buildings give this Dutch island its charm. Don't miss the colorful floating market, a short walk from Queen Emma Pontoon Bridge. A World Heritage site, Punda preserves hundreds of national monuments, including Fort Amsterdam, the Governor's Palace, Mikve Israel-Emanuel Synagogue-one of the first in the New World-and the colorful Penha building.

Panama City blends a shimmering skyline with cobblestone streets, rooftop bars, and centuries-old ruins. Founded in 1519, Panamá Viejo was abandoned in the mid-17th century and replaced by Casco Viejo; together they are a UNESCO Cultural World Heritage site. Visit the Panama Canal Museum for exhibits on the "Big Ditch," and honor the 22,000 workers who died building it at Plaza de Francia.