Rome offers endless choices: enjoy street performers at the Spanish Steps, wine and people-watching in colorful Trastevere, or the city's rich history and architecture. St. Peter's Basilica is a full-day visit, with the Sistine Chapel and panoramic views from the dome. Don't miss the Trevi Fountain, the Colosseum, and Aventine Hill, which overlooks the Imperial Palaces ruins and the Circus Maximus.

Discover chic Positano, with its relaxed sophistication, white Moorish-style houses on steep slopes, and a sparkling bay dotted with colorful fishing boats. Then visit enchanting Amalfi to see the 12th-century Capuchin monastery, the 11th-century Cathedral and cloister, and explore on your own. Browse Positano's boutiques for locally made cotton clothes or find souvenirs in Amalfi. Enjoy fresh seafood, pasta, pastries, and espresso in a stunning seaside mountain setting.

Discover Reggio Calabria, where the Ionian Sea meets the Aspromonte. Explore hillside villages, sunlit vineyards, and authentic Calabrian cuisine rooted in tradition. Walk the elegant Lungomare Falcomatà and visit the Museo Nazionale to see the Bronzi di Riace, famed ancient Greek sculptures. Tour the Aragonese Castle and uncover the city's deeper history, from Norman roots to even older origins.

Destroyed by a 17th-century earthquake, Catania has been beautifully restored and offers ancient churches, castles, amphitheaters, lush gardens, and elegant palazzos. Visit 13th-century Ursino Castle, once on the coast before earthquakes and eruptions reshaped the land. Inland, explore Villa Romana del Casale, a 4th-century UNESCO site famed for some of the finest Roman mosaics.

Known as the "Pearl of the Adriatic," Dubrovnik was founded in the 7th century by a group of refugees from Epidaurum (today's Cavtat). It is known worldwide for its unique marble-paved squares, tall houses, steep-cobbled streets and fountains. The city walls, once used to as protection against its enemies, now keep motorists at bay in this picturesque town. UNESCO named the Old City a World Heritage Site, and Dubrovnik's beautiful historic sites have been restored to their former glory.

On the west coast of Istria, this fishing port rises from the Adriatic like a cluttered fortress, with tightly packed Venetian houses, cobbled streets, and the hilltop Church of St. Euphemia. Its egg-shaped Old Town offers boutiques, cafés, galleries, bistros, and restaurants with Italian food and local wines. Nearby, the Istrian hinterland has medieval hill villages, vineyards, olive groves, and truffles.

From Fusina, journey to Venice, where you'll witness the Grand Canal, lined with enchanting Renaissance architecture. Art lovers can visit the Peggy Guggenheim Collection or the Doge's Palace, a Gothic masterpiece. Savor Venetian cuisine at a traditional trattoria, sampling fresh local dishes. History enthusiasts can also peruse St Mark's Basilica, a marvelous 18th-century cathedral adorned with sculptures, mosaics and bas-reliefs representing Italian sophistication.

Split is the largest Croatian city on the Adriatic coast. It is famous for Diocletian's Palace, built as the Roman emperor's retirement home; its stone structure, grounds, and cellars are a major highlight. Other sights include the Cathedral of St. Duje, on the remains of an ancient shrine said to be the world's oldest, and the Mestrovic Gallery, featuring works by Croatian sculptor Ivan Mestrovic in his former home and atelier.

Kotor is a coastal town in Montenegro, located in a most secluded part of the Gulf of Kotor. The old port, surrounded by an impressive city wall built by the House of Nemanjicc, is very well preserved and is a UNESCO World Heritage site. Numerous other attractions include the Cathedral of Saint Tryphon in the old town (built in 1166), and ancient walls which stretch directly above the city. Nightlife also attracts tourists to Kotor with pubs, taverns, cafes, and nightclubs.

Legendary Corfu is a lush and romantic island, written about by Homer in his famous Odyssey. The island's history is full of battles, indicative of Corfu's turbulent position that lasted until modern times with unification with modern Greece in 1864. Corfu offers a combination of cosmopolitan and time-honored Greece. As well as a flower-strewn countryside and Adriatic-style villages, Corfu has splendid coastal scenery and some excellent secluded beaches.

Step back in time at Ancient Olympia, the birthplace of the Olympic Games - now deemed a UNESCO World Heritage Site. Relive the roaring cheers of the spectators as the athletes took their marks on the marble starting blocks, and picture the temples, the treasuries, the porticoes and statues as they were.

Santorini's dramatic views-whitewashed houses clinging to the caldera, plus white, red, and black-sand beaches-make it one of the world's most photographed places. Visit Ancient Akrotiri, a town preserved by ash from an eruption 3,600 years ago, and take a day trip to Palea (Old) Kameni and Nea (New) Kameni, two black-lava islands in the center of the Santorini basin.

Piraeus is the gateway to Athens, the "Cradle of Western Civilization," famed for its lasting cultural and political influence. Driven by tourism and the 2004 Olympics, Greece has redeveloped many sites. Athens remains a historian's delight, with the Acropolis, Parthenon, Plaka's winding streets, the Temple of Olympian Zeus, the Temple of Athena Nike, and the Archaeological Museum's renowned ancient artifacts.