Rome offers endless choices: enjoy street performers at the Spanish Steps, wine and people-watching in colorful Trastevere, or the city's rich history and architecture. St. Peter's Basilica is a full-day visit, with the Sistine Chapel and panoramic views from the dome. Don't miss the Trevi Fountain, the Colosseum, and Aventine Hill, which overlooks the Imperial Palaces ruins and the Circus Maximus.

Leave town to discover five stunning, colorful cliffside towns on the coast. Hike the trail linking them or take a boat tour to see them from the water. Go ashore to explore a picturesque town and its castle, or visit Porto Venere, a colorful harbor town with breathtaking views and the Church of San Pietro. Once a playground and inspiration for poets from Dante to Byron and Shelley.

Located in southeastern France, today's Marseille is a far cry from the sleepy villages it once inspired in Cézanne's paintings. With more than a million people, the city remains the cosmopolitan and exuberant capital of southern Europe, with its picturesque Old Quarter, lively sidewalk cafes and shops, and Romanesque-Byzantine Notre Dame de la Garde Basilica, overlooking the steep cliffs and offering a bird's eye view of the city's colorful "quartiers" stretching down toward the sea.

Experience Costa Brava and understand why Salvador Dalí and others have long been inspired by its beaches and coves. Spend a day in the warm sand of La Fosca or learning about the history of this fishing village in Museu de la Pesca or simply taking in the Mediterranean air while walking down the promenade. Just an hour north of the city, you can visit the extraordinary Dalí Theatre-Museum in Figueres. The museum holds works done from his adolescence to the last years of his life.

Málaga, on Spain's Costa del Sol, is the region's capital and a popular holiday base. It is Picasso's birthplace, and his works are displayed in the Museo Picasso in the Palacio de Buenavista. Visitors can also sample sweet Málaga dessert wines from nearby hillside vineyards. The city is a pleasant place to explore and a common starting point for trips to Granada and the Alhambra in the Sierra Nevada foothills.

Gibraltar, located near the southernmost tip of the Iberian Peninsula, overlooks the Strait of Gibraltar, known to ancient mariners as the Pillars of Hercules. Historically, Gibraltar has been an important base for the British Royal Navy. It is most famous for the geological formation, the Rock of Gibraltar and its tribe of Barbary Apes. Despite long sieges throughout its history, it seemed nothing could destroy the Rock or its people, leading to the phrase "solid as the Rock of Gibraltar."

Lisbon, said to have been founded by Ulysses as Olisipo, is one of Europe's most fascinating cities. A devastating 1755 earthquake destroyed much of it, and the Baixa was rebuilt in neo-classical style, now the city's heart. Overlooking the Tagus, the "City of Explorers" offers districts like Alfama, with Moorish lanes, and Bairro Alto, where you can hear Fado. Nearby are the palaces of Queluz and Sintra.